Co-occurrence of mutations in 200 AML samples

Directions: Samples are plotted on the circumference of the circle according to their mutations. Fibers crossing the circle show the co-occurrence of different mutations in a specific sample.

Mousing-over a sample will highlight co-occurring mutations, and bring up relevant clinical information for that sample.

Mousing-over a gene/category name will highlight all co-occuring mutations in that gene/categories.

More clinical annotation for the AML cases can be found in Supplemental Table 1.

Note: Interactive visualization requires a recent web browser (e.g. Internet Explorer 9 and higher, Google Chrome, Firefox 3.6 and higher, or Safari 4 and higher).

coocurrence contrast:
Powered by D3, Hierarchical Edge Bundling
Color legend of p-values:
p ≤ 0.01
0.01 < p ≤ 0.05
0.05 < p ≤ 0.1

Designed by Hsin-Ta Wu, Max Leiserson, Jason Hu, Ben Raphael

Department of Computer Science, and Center for Computational Molecular Biology, Brown University

Archived versions of this graph can be found here